Publication

In collaboration with academic research groups, there is part of a number of publications on specific Blockmirs and their potential therapeutic use:



Targeting vascular endothelial-cadherin in tumor-associated blood vessels promotes T cell-mediated immunotherapy

 

Yang Zhao, Kaka Ting, Jia Li, Victoria C Cogger, Jinbiao Chen, Anna Johansson-Percival, Shin Foong Ngiow, Jeff Holst, Georges E. R. Grau, Shom Goel, Thorleif Moller, Elisabetta Dejana, Geoffrey W McCaughan, Mark J. Smyth, Ruth Ganss, Mathew A Vadas and Jennifer R Gamble

 

Cancer Research DOI: 10.1158/0008-5472.CAN-16-3129

 


Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin–restricted miRNA antagonists of miR-27

 

Jennifer A. Young, Ka Ka Ting, Jia Li, Thorleif Moller, Louise Dunn, Ying Lu, Angelina J. Lay, Joshua Moses, Leonel Prado-Lourenço, Levon M. Khachigian, Martin Ng, Philip A. Gregory, Gregory J. Goodall, Anna Tsykin, Ilana Lichtenstein, Christopher N. Hahn, Nham Tran, Nicholas Shackel, James G. Kench, Geoffrey McCaughan, Mathew A. Vadas and Jennifer R. Gamble

 

Blood 2013 122:2911-2919; doi: https://doi.org/10.1182/blood-2012-12-473017

 


Therapeutic regulation of VE-cadherin with a novel oligonucleotide drug for diabetic eye complications using retinopathy mouse models

 

Ka Ka Ting, Yang Zhao, Weiyong Shen, Paul Coleman, Michelle Yam, Tailoi Chan-Ling, Jia Li, Thorleif Moller, Mark Gillies, Mathew A. Vadas, Jennifer R. Gamble

 

Diabetologia. 2018 Nov 15. doi: 10.1007/s00125-018-4770-4.

 

The VE-Cadherin/β-catenin signalling axis regulates immune cell infiltration into tumours

Yang Zhao, Jia Li, KaKa Ting, Jinbiao Chen, Paul Coleman, Ken Liu, Li Wan, Thorleif Moller, Mathew A. Vadas, Jennifer R. Gamble

 

Cancer Letters, Volume 496, 1 January 2021, Pages 1-15

 


Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice


Jia Li Yang Zhao, Jaesung Choi, Ka Ka Ting, Paul Coleman, Jinbiao Chen, Victoria C. Cogger, Li Wan, Zhongsong Shi, Thorleif Moller, Xiangjian Zheng, Mathew A. Vadas, Jennifer R. Gamble

 

PLOS Biology | https://doi.org/10.1371/journal.pbio.3000734 June 5, 2020